Northwestern University Feinberg School of Medicine
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Cancer Epigenetics & Nuclear Dynamics Members

The Cancer Epigenetics & Nuclear Dynamics (CEND) program focuses on how nuclear dynamics and information flow within the cell are co-opted in cancer through altered genetic and epigenetic mechanisms.

Vafabakhsh, Reza

Vafabakhsh, Reza

Associate Professor

Bio

Our laboratory research is directed along two main avenues: Firstly, we are dedicated to characterizing the mechanisms underlying the activation of G protein-coupled receptors (GPCRs) a... [more]

Varma, Dileep

Varma, Dileep

Assistant Professor

Bio

The research in our lab is directed at understanding the molecular mechanisms that are involved in controlling and regulating proper kinetochore microtubule attachments in human cells. The malfunction... [more]

Wang, Lu

Wang, Lu

Assistant Professor

Bio

The recent genome-wide sequencing analysis have identified a series of novel somatic genetic alterations in patients with relevance to pathogenesis, prognostication, and therapy. Notably, these includ... [more]

Wang, Xiaozhong

Bio

Genetic manipulations in mouse embryonic cells provide a very useful platform to unveil in vivo functions of human genes, particularly for those health-related genes such as cancers. The Wang labor... [more]

Weiss, Eric

Weiss, Eric

Associate Professor

Bio

Dr. Weiss's laboratory is interested in understanding how protein kinase signaling pathways coordinate cytoskeleton organization, membrane traffic, and gene expression to define cell architecture. ... [more]

Wignall, Sadie

Wignall, Sadie

Associate Professor

Bio

Proper segregation of chromosomes during mitosis and meiosis depends upon the formation of a bipolar spindle. In most cell types, duplicated centrosomes contribute to spindle assembly by nucleating m... [more]

Yang, Rendong

Yang, Rendong

Associate Professor

Bio

The Yang Lab is interested in the integrative analysis of large-scale datasets to understand the initiation and progression of diseases. The research projects involve in the development of highly accu... [more]

Yi, Yang

Yi, Yang

Assistant Professor

Bio

The goal of Dr. Yi's research centers on uncovering the previously unrecognized functions of epigenetic modification during normal and pathological bioprocesses, and decoding the potential crosst... [more]

Yue, Feng

Yue, Feng

Professor

Bio

The long-term goal of Dr. Yue's group is to use a combination of high throughput genomics, computational modeling, and functional assays to study how genetic variants contribute to the pathogenes... [more]

Zhang, Christine

Zhang, Christine

Assistant Professor

Bio

My lab is interested in understanding how genetic and epigenetic factors cooperates to initiate leukemogenesis and other hematological malignancies.