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Northwestern University Feinberg School of Medicine

Lymphoma

Lymphoma is cancer that begins in cells of the lymph system. The lymph system is part of the immune system, which helps the body fight infection and disease. Because lymph tissue is found all through the body, lymphoma can begin almost anywhere.

The two main types of lymphoma are Hodgkin lymphoma and non-Hodgkin lymphoma (NHL). These can occur in both children and adults.

Most people with Hodgkin lymphoma have the classic type. With this type, there are large, abnormal lymphocytes (a type of white blood cell) in the lymph nodes called Reed-Sternberg cells. Hodgkin lymphoma can usually be cured.

There are many different types of NHL that form from different types of white blood cells (B-cells, T-cells, NK cells). Most types of NHL form from B-cells. NHL may be indolent (slow-growing) or aggressive (fast-growing). The most common types of NHL in adults are diffuse large B-cell lymphoma, which is usually aggressive, and follicular lymphoma, which is usually indolent.

Mycosis fungoides and the Sézary syndrome are types of NHL that start in white blood cells in the skin. Primary central nervous system lymphoma is a rare type of NHL that starts in white blood cells in the brain, spinal cord or eye.

The treatment and the chance of a cure depend on the stage and the type of lymphoma. Browse the types to the right to learn more. We also treat Burkitt lymphoma, cutaneous t-cell lymphoma (CTCL) and Waldenstrom's macroglobulinemia.

Our Experts

Our experts work together in a multidisciplinary team (including dedicated, talented nursing staff and Lurie Cancer Center’s Supportive Oncology Team) to help create a comprehensive, individualized treatment plan and provide you with exceptional support. Get to know our physicians and the many other experts who will play an important role in your care.

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Clinical Trials

The Lurie Cancer Center is typically involved in more than 300 clinical trials at a given time, covering a broad range of subjects that may be relevant to your diagnosis. Browse our clinical trials to participate and help test new treatments.

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Patient Support

We offer a number of services to help patients and their families cope with the challenges of cancer treatment.

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Featured Programs

Cutaneous Lymphoma Clinic

Our clinic doctors are experts in the latest diagnostic techniques and in cutting-edge therapies for treating cutaneous lymphomas. Therapy plans are tailored to each patient.

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Hematopoietic Stem Cell Transplant Program

Our Hematopoietic Stem Cell Transplant Program is the leader in volume and types of transplants, averaging over 250 transplantations per year, resulting in survival rates consistently exceeding the national survival rate.

Stem cell transplants are regularly used to treat Hodgkin's lymphoma and non-Hodgkin's lymphomas, such as large b-cell lymphoma, mantle cell lymphoma and cutaneous t-cell lymphoma.

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Car T-Cell Therapy Program

Chimeric antigen receptor, or CAR T-cell therapy, uses a patient’s own immune system to target and destroy cancer cells. Lurie Cancer Center is a leader in advancing this highly specialized form of immunotherapy through FDA-approved CAR T-cell treatments and cutting-edge clinical trials.

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