Northwestern University Feinberg School of Medicine
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Translational Research in Malignancy Members

The Translational Research in Malignancy (TRIM) program is a highly interactive translational cancer research program. Its main objective is to conduct studies centered on molecular mechanisms of cancer progression and therapeutic resistance and to translate basic science and preclinical discoveries into early diagnosis, biomarkers, and cancer therapeutics.

Choi, Jaehyuk

Choi, Jaehyuk

Associate Professor

Bio

We study incurable skin cancers with a primary focus on cutaneous T cell lymphoma. We are using human and animal models with two goals. We seek to determine 1) the molecular basis of the aberrant... [more]

Dinner, Shira N

Dinner, Shira N

Associate Professor

Bio

Dr. Dinner is a clinical researcher with an interest in novel molecularly targeted therapies for leukemias, in particular acute lymphoblastic leukemia (ALL). Development of future clinical t... [more]

Eklund, Elizabeth A.

Bio

The focus of my laboratory is to understand the key events in normal myelopoiesis and how leukemia-associated mutations derange these processes during leukemogenesis.

Godley, Lucy

Godley, Lucy

Professor

Bio

The Godley laboratory studies the molecular pathways that drive hematopoietic malignancies, with a focus on understanding how germline predisposition alleles contribute to individual and family risk a... [more]

Gordon, Leo I.

Bio

Novel signaling pathways in lymphoma, using cell lines and animal model systems. More specifically, our research focuses on the biology of reactive oxygen species signaling pathways in lymphoma. Activ... [more]

Gradishar, William J.

Bio

My research focuses on the development of novel therapeutics for the treatment of breast cancer.

Guitart, Joan

Bio

Cutaneous T-cell lymphoma, Dermatopathology, Skin cancer prevention and detection.

Heimberger, Amy

Bio

I am a physician-scientist and a board-certified Neurosurgeon with extensive training and experience in the field of immunology. My laboratory is focused on elucidating the mechanisms of tumor-mediate... [more]

Horbinski, Craig

Bio

My career as a physician-scientist and investigative neuropathologist allows me to conduct research that will enhance our understanding of how key driver mutations, like mutant IDH1, affect glioma bio... [more]

Horiuchi, Dai

Horiuchi, Dai

Assistant Professor

Bio

Our research aims to identify and validate novel therapeutic strategies to significantly lower the mortality rates associated with triple-negative breast cancer (TNBC), which represents one ... [more]