Leo I. Gordon, MD
Professor, Medicine, Hematology Oncology Division; Feinberg School of Medicine
Research Program
- Translational Research in Malignancy (TRIM)
Cancer-Focused Research
Novel signaling pathways in lymphoma, using cell lines and animal model systems. More specifically, our research focuses on the biology of reactive oxygen species signaling pathways in lymphoma. Active investigations include: 1) the biology of the lactone diterpenoids in lymphoma; 2) the study of nicotinamide as a mediator of apoptosis in lymphoma cell lines, 3) The characterization of cholesterol efflux pumps as a target in lymphoma, in collaboration with Dr. Colby Shad Thaxton from the Department of Urology and the Northwestern University Center of Cancer Nanotechnology excellence; 4) the study of hypoxia inducible factor (HIF) in lymphoma, in collaboration with Dr. Paul Schumacker.