Cancer & Physical Sciences Members
The Cancer & Physical Sciences Program unites fundamental chemistry, physical sciences and bioengineering groups that focus on developing cancer-relevant therapeutic and diagnostic agents using nano-scale materials and physical sciences approaches.
Hoffman, Brian
Professor
Bio
We determine the catalytic mechanisms of metalloenzymes through the development and implementation of electron-nuclear double resonance (ENDOR) spectroscopy, a combination of NMR and EPR.ÂÂ
Horvath, Curt
Professor
Bio
My laboratory focuses on the molecular events controlling inducible gene regulation, with focus on the production of and response to cytokines and especially interferon and IFN-JAKSTAT signal transdu... [more]
Jin, Jing
Assistant Professor
Bio
Our research focuses on the synthetic design of recombinant fusion proteins for biotherapeutic, diagnostic, and disease modeling purposes. One of the general themes of our designs is to achieve target... [more]
Joester, Derk
Associate Professor
Bio
My research has been focused on understanding the mechanisms by which cells grow crystals; both in cell culture (see section C.2), and in cell-free, in vitro model systems (section C.3). An integral p... [more]
Kelleher, Neil
Professor
Bio
Natural Products Discovery and Biosynthesis, Top Down Mass Spectrometry, and Epiproteomics.
Kelley, Shana
Professor
Bio
Our research group works at the interface of Chemistry, Biology, Engineering and Medicine to develop new technologies for therapeutic discovery and development as well as new diagnostic approaches. U... [more]
Kim, Dong-Hyun
Associate Professor
Bio
My research has been focused on therapeutic nano-carriers for treatment of various types of cancer. Nanoparticles and their hybrid derivatives have been exploited as vectors for drug delivery, therape... [more]
Leonard, Joshua
Professor
Bio
My research group works at the interface of systems biology and synthetic biology in order to probe and program the function of complex, multicellular systems to develop transformative biotechnologies... [more]
Meade, Thomas
Professor
Bio
Professor Meade Lab's research focuses on inorganic coordination chemistry for the study of molecular imaging of in vivo gene expression and intracellular messengers, transition metal enzyme inhibitor... [more]
Mirkin, Chad
Professor
Bio
Prof. Mirkin has pioneered the use of nanoparticle-biomolecule conjugates as synthons in materials science and the development of many nanoparticle-based extra- and intracellular biodiagnostic and the... [more]