Tumor Environment & Metastasis Members
The Tumor Environment & Metastasis (TEAM) Program uses an integrative approach to elucidate key molecular interactions between tumor cells and components of the host stromal microenvironment including matrix, vascular structures and cells of the immune system.
Eisenbarth, Stephanie
Professor
Bio
Red blood cell (RBC) transfusion is a powerful therapeutic tool and the most common form of transplantation in clinical practice, yet the immune system of the transfusion recipient can respo... [more]
Fang, Deyu
Professor
Bio
The current application is to delineate the cellular and molecular mechanisms underlying USP22 (ubiquitinspecific peptidase 22) in Regulatory T (Treg) cell hemostasis and functions. Our preliminary da... [more]
Folsch, Heike
Research Associate Professor
Bio
Understanding how epithelial cells establish and maintain apical-basolateral polarity through continuously sorting transmembrane proteins to their correct target domains. Our focus is on sorting event... [more]
Fourati, Slim
Assistant Professor
Bio
My research focuses on the use of bioinformatic analysis of high-throughput data (like RNA-Sequencing, Flow cytometry) to identify biological mechanisms associated with the immune response to perturba... [more]
Gelfand, Vladimir
Professor
Bio
Cytoskeleton, motor proteins, cell movement, microtubules, actin, kinesin, dynein, myosin, neurodegenerative diseases.
Gottardi, Cara
Associate Professor
Bio
Expertise in how cells adhere to each other, what constitutes dynamic versus static adhesion at the molecular level, and how the state of cell-cell adhesion is interpreted by the nucleus to control ge... [more]
Green, Kathleen
Professor
Bio
Our work has established that in addition to playing a critical role in cell-cell adhesion, desmosomal cadherins serve as signaling scaffolds that dictate cell behavior and control the balance of prol... [more]
Heimberger, Amy
Professor
Bio
I am a physician-scientist and a board-certified Neurosurgeon with extensive training and experience in the field of immunology. My laboratory is focused on elucidating the mechanisms of tumor-mediate... [more]
Horvath, Curt
Professor
Bio
My laboratory focuses on the molecular events controlling inducible gene regulation, with focus on the production of and response to cytokines and especially interferon and IFN-JAKSTAT signal transdu... [more]
Jin, Jing
Assistant Professor
Bio
Our research focuses on the synthetic design of recombinant fusion proteins for biotherapeutic, diagnostic, and disease modeling purposes. One of the general themes of our designs is to achieve target... [more]