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Clinical Trial NU 12CC12

A Randomized Open-Label Pilot Trial to Evaluate the Safety and Efficacy of Repetitive Transcranial Magnetic Stimulation in Cancer Patients with Depression and Anxiety
Principal Investigator
Mehmet Dokucu
  • Status: Accepting New Patients
  • Study Type: Therapeutic, Treatment
  • Protocol No:.NU 12CC12
The purpose of this study is to test the safety and tolerability of left- and right-sided rTMS as a treatment for depression in the cancer population.
Cancer patients are at high risk for developing depression, both during the illness and while in remission. Depression in cancer patients is associated with lower quality of life and poor treatment adherence. Current treatment options include psychotherapy (a.k.a. "talk therapy"), medications, or a combination of both. A new technique called Transcranial Magnetic Stimulation (rTMS)is being used to treat some patients with depression, who have no other accompanying medical illnesses. The reason for this study is to see if rTMS may be effective in treating cancer-related depression. Transcranial Magnetic Stimulation (rTMS) is a technique currently being used to treat patients with depression, but do not have an accompanying medical illness (such as cancer). rTMS alters brain activity by applying a magnetic field to the outside of a patient's intact scalp. Two methods of delivering rTMS has become standard: One method includes placement of the magnet externally on the left side of the head, and the other includes placement of the magnet externally on the right side of the head.
Some of the eligibility criteria include:
  • Participants must be between 22-70 years old.
  • Participants must have a diagnosis of cancer that is in remission.
  • Participants must have a diagnosis of depression.
  • Participant's depression must have failed to improve after at least 1 prior antidepressant medication .
Note: This is only a partial list of eligibility criteria. Please contact the Lurie Cancer Center for complete screening information if you are interested in this clinical trial.
Description of Treatment
Participants in this study will be randomized to one of two groups: One group will receive rTMS applied to the left side of the head and the other group will receive the rTMS applied to the right side of the head. Participants will receive rTMS once a day for 40 minutes, 5 days a week, for 6 weeks in total.
Clinical Trials Recruitment Nurse
Robert H. Lurie Comprehensive Cancer Center

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last updated: 19-Oct-17 07:37 AM


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