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Northwestern University Feinberg School of Medicine

Awards Support Innovative Prostate Cancer Research

The Robert H. Lurie Comprehensive Cancer Center’s SPORE in Prostate Cancer and Polsky Urologic Cancer Institute announce the following awards in support of innovative prostate cancer research:

SPORE Supported Awards

Abdulkadir

Targeting Asparagine-dependency in TP53-mutant Prostate Cancer

Principal Investigator:  Sarki Abdulkadir, MD, PhD
Professor, Urology

Bagci

AI-Powered Hybrid Multidimensional MRI (HM-MRI) to
Improve Prostate Cancer Diagnosis

Principal Investigator: Ulas Bagci, PhD
Associate Professor, Radiology

Ross

Cooper

A Classifier Integrating Digital Histologic Biomarkers and Clinical Features for Enhanced Active Surveillance Risk Stratification in Prostate Cancer

Principal Investigators:

Ashley Ross, MD, PhD
Associate Professor, Urology

Lee Cooper, PhD
Associate Professor, Pathology

 Graham

Prostate cancer cell-mediated reprogramming of the tumor microenvironment in metastasis

Principal Investigator: Mindy Graham, PhD
Research Assistant Professor, Urology

Lee-Chang

Development of a B-Cell Therapy (BVax) for Prostate Cancer 

Principal Investigator:  Catalina Lee-Chang, PhD
Assistant Professor, Neurological Surgery

Radhadrishnan

Molecular Mechanisms of Ligand-Independent Transcriptional Activation by Androgen Receptor

Principal Investigator: Ishwar Radhakrishnan, PhD
Professor, Molecular Biosciences

Patnaik

Targeting ENPP1-STING pathway to enhance PARP inhibitor in prostate cancer

Principal Investigator: Akash Patnaik, MD, PhD
Associate Professor: Medicine (University of Chicago)

Zhang

CD73 blockade therapy sensitizing PARP inhibition in advanced prostate cancer

Principal Investigator: Bin Zhang, MD, PhD
Professor, Medicine

Thaxton

Three-In-One Radiosensitizer for Cancer Therapy

Principal Investigator: C. Shad Thaxton, MD, PhD
Associate Professor, Urology

Vanderweele

BAT and Docetaxel to Prime Sensitivity to Cytotoxic Therapy

Principal Investigator: David VanderWeele, MD, PhD
Associate Professor, Medicine

 

Polsky Urologic Institute Supported Awards

Cao

 

Ketone drink inhibits prostate cancer by targeting EZH2

Principal Investigator: Qi Cao, PhD
Associate Professor, Urology

Patel

Cooper

Histopathologic Features of False Negative Multiparametric  MRI Lesions in Patients with Clinically Significant Prostate Cancer -a Digital Pathology-Based Approach

Principal Investigators: 

Hiten Patel, MD
Assistant Professor, Urology

Lee Cooper, PhD
Associate Professor, Pathology

Yi

Mechanism underlying the regulation of m6A mRNA Methylation in CRPC

Principal Investigator: Yang Yi, PhD
Assistant Professor, Urology