Awards Support Innovative Prostate Cancer Research

A novel role for EZH2 in PARP regulation and PARPi resistance in prostate cancer

Principal Investigator:  Qi Cao, PhD
Associate Professor, Urology

Enhanced TCR-Engineered T Cell Immunotherapy in Combination with Epigenetic Modulation for Prostate Cancer

Principal Investigator: Richard Koya, MD, PhD (University of Chicago);
Professor, Obstetrics and Gynecology

Role of BAP1 complexes in prostate cancer

Principal Investigator: Lu Wang, PhD 
Assistant Professor, Biochemistry and Molecular Genetics

Elucidating the Impact of Androgen Ablation on Innate Immunity in Prostate Cancer

Principal Investigator: Akash Patnaik, MD, PhD  (University of Chicago)
Assistant Professor, Medicine

Improving Response Rates to PARP Inhibitors in Advanced Prostate Cancer Through Combination Therapy with Sacituzumab Govitecan

Principal Investigator:  Sarah Fenton, MD, PhD
Assistant Professor, Medicine 

Prostate cancer cell-mediated reprogramming of the tissue microenvironment in visceral metastases

Principal Investigator: Mindy Graham, PhD
Research Assistant Professor, Urology

Discovery and development of molecular glue degraders targeting androgen receptor splice variants driven prostate cancer

Principal Investigator: Xiaoyu Zhang, PhD
Assistant Professor, Chemistry  

Targeting epigenome and PARPness regulating prostate cancer cell fate 

Principal Investigators:

Debabrata (Debu) Chakravarti, PhD;
Professor, Obstetrics and Gynecology

Brandon Parker, PhD
Research Assistant Professor, Obstetrics and Gynecology 

Integrated Long-Read Single-Cell Genomic and Transcriptomic Sequencing (LscDuo-seq) to Unravel the Landscape of Chemoresistance in Prostate Cancer

Principal Investigator: Rendong Yang, PhD
Associate Professor, Urology

Metabolic and Cytoskeletal Regulation of Cell Proliferation and Metastasis in Prostate Cancer

Principal Investigator: Dileep Varma, PhD
Assistant Professor, Biochemistry and Molecular Genetics