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Quantitative Data Sciences Core (QDSC)

Description

The QDSC combines the former Biostatistics Core Facility and the Cancer Informatics Core Facility. The core will collaborate in three main areas - Biostatistics, Bioinformatics and Clinical Informatics.

Leadership

Director:
Alfred W. Rademaker PhD
Professor, Department of Preventive Medicine
Director Division of Biostatistics

Associate Director of Biostatistics:
Denise M. Scholtens PhD
Associate Professor
Preventive Medicine
Neurological Surgery
Associate Director
Division of Biostatistics

Associate Director of Bioinformatics:
Matthew J. Schipma, PhD
Research Assistant Professor
Biochemistry and Molecular Genetics

Associate Director of Clinical Informatics:
Firas H. Wehbe MD PhD
Assistant Professor
Preventive Medicine
Division of Health and Biomedical Informatics


Expertise & Activities

Biostatistics:

  • Early phase clinical trial design
  • Research study design, including sample size power calculations
  • Wide range of statistical analyses for basic science, population-based and clinical data

Bioinformatics:

  • Pipelines for NGS Analysis (ChIP-seq and RNA-seq now, more to come)
  • Pathway and Gene Set Enrichment Analysis
  • Study Design and Consultation
Clinical Informatics:
  • Software development for clinical trial informatics
  • Life science focused web based development
  • Disease based secure database and informatics tools for human subject research
  • NMEDW clinical data analysis and reporting
  • Machine learning and NLP based analysis of clinical text
  • Coordination with clinical partners on EMR-based research and integration

In addition to area-specific expertise within the core, core members will engage in the following general activities:

  • Collaboration with cancer center members across all programs;
  • Collaboration with cancer center members on both the Chicago and Evanston campuses
  • Discussion about research objectives and hypotheses;
  • Writing informatics and statistical sections for grant applications;
  • Active collaboration through funded grant activity;
  • Active co-authoring of research findings
  • Interaction and integration with other cancer center cores as needed;
  • Interaction and integration but not overlapping with cores and entities external to the cancer center as needed (NUCATS, IPHAM, CPS, CDSI, BCC, NUGENE, NUSeq);
  • Development of new methodology in Biostatistics and Biomedical Analytics
  • Development and review of cancer related protocols;
  • Education through individual contact, group seminars, journal clubs and fellow/junior faculty development;

In addition to the co-directors, each area includes faculty and staff who will work with Lurie Cancer Center members in providing expertise as needed.

Contact:

qdsc_rhlccc@northwestern.edu

If you are ready to submit a request for QDSC services please fill out our intake form.

Core administrator:
Tameka Brannon
Department of Preventive Medicine
680 N. Lake Shore Dr., St. 1400
Chicago IL 60611
t-mann@northwestern.edu
312.503.2288

Biostatistics:
680 N. Lake Shore Dr., St. 1400
Chicago IL 60611
312.503.2288 or 312.908.1970

Bioinformatics:
Rubloff Building 11th floor, 11-144
750 N. Lake Shore Dr.
Chicago IL 60611
312.503.5324

Clinical Informatics:
Rubloff Building 11th floor, 11-166
750 N. Lake Shore Dr.
Chicago IL 60611
312.503.2311