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Quantitative Data Sciences Core (QDSC)


The QDSC combines the former Biostatistics Core Facility and the Cancer Informatics Core Facility. The core will collaborate in three main areas - Biostatistics, Bioinformatics and Clinical Informatics.


Alfred W. Rademaker PhD
Professor, Department of Preventive Medicine
Director Division of Biostatistics

Associate Director of Biostatistics:
Denise M. Scholtens PhD
Associate Professor
Preventive Medicine
Neurological Surgery
Associate Director
Division of Biostatistics

Associate Director of Bioinformatics:
Matthew J. Schipma, PhD
Research Assistant Professor
Biochemistry and Molecular Genetics

Associate Director of Clinical Informatics:
Firas H. Wehbe MD PhD
Assistant Professor
Preventive Medicine
Division of Health and Biomedical Informatics

Expertise & Activities


  • Early phase clinical trial design
  • Research study design, including sample size power calculations
  • Wide range of statistical analyses for basic science, population-based and clinical data


  • Pipelines for NGS Analysis (ChIP-seq and RNA-seq now, more to come)
  • Pathway and Gene Set Enrichment Analysis
  • Study Design and Consultation
Clinical Informatics:
  • Software development for clinical trial informatics
  • Life science focused web based development
  • Disease based secure database and informatics tools for human subject research
  • NMEDW clinical data analysis and reporting
  • Machine learning and NLP based analysis of clinical text
  • Coordination with clinical partners on EMR-based research and integration

In addition to area-specific expertise within the core, core members will engage in the following general activities:

  • Collaboration with cancer center members across all programs;
  • Collaboration with cancer center members on both the Chicago and Evanston campuses
  • Discussion about research objectives and hypotheses;
  • Writing informatics and statistical sections for grant applications;
  • Active collaboration through funded grant activity;
  • Active co-authoring of research findings
  • Interaction and integration with other cancer center cores as needed;
  • Interaction and integration but not overlapping with cores and entities external to the cancer center as needed (NUCATS, IPHAM, CPS, CDSI, BCC, NUGENE, NUSeq);
  • Development of new methodology in Biostatistics and Biomedical Analytics
  • Development and review of cancer related protocols;
  • Education through individual contact, group seminars, journal clubs and fellow/junior faculty development;

In addition to the co-directors, each area includes faculty and staff who will work with Lurie Cancer Center members in providing expertise as needed.


If you are ready to submit a request for QDSC services please fill out our intake form.

Core administrator:
Tameka Brannon
Department of Preventive Medicine
680 N. Lake Shore Dr., St. 1400
Chicago IL 60611

680 N. Lake Shore Dr., St. 1400
Chicago IL 60611
312.503.2288 or 312.908.1970

Rubloff Building 11th floor, 11-144
750 N. Lake Shore Dr.
Chicago IL 60611

Clinical Informatics:
Rubloff Building 11th floor, 11-166
750 N. Lake Shore Dr.
Chicago IL 60611