Lurie Cancer Center Member
David J Klumpp, PhD
Associate Professor, Microbiology-Immunology; Feinberg School of Medicine
Cancer Control & Survivorship
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Dr. Klumpp's research program focuses on microbial modulation of host responses with an emphasis on bladder inflammation. Chronic inflammation plays a central role in many cancers, so understanding organ-specific host responses to inflammation is critical to identifying cancer risk factors and identifying novel therapeutic interventions. Moreover, bladder cancer is associated with high morbidity and high costs. A leading therapy for bladder cancer is a controlled bladder infection that results in robust inflammation and a resulting immune response that clears the cancer. Understanding bladder inflammatory responses will enhance our capacity to shape the immune responses during cancer therapy to improve patient outcomes.