Lurie Cancer Center Member
SonBinh T Nguyen, PhD
Professor, Chemistry; Judd A. and Marjorie Weinberg College of Arts and Sciences
Cancer and Physical Sciences
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Dr. Nguyen research group focuses on the design of polymer-based smart drug delivery vehicles for the targeted treatment of cancer. Highly tunable, well-defined block copolymers made using Dr. Nguyen's methods possess a high density of chemotherapeutic drugs on the hydrophobic block. This segment of the molecule is attached to a hydrophilic block that confers aqueous solubility on these often-insoluble drugs. These copolymer assemblies are then made into nanoscale core_shell polymer nanoparticles (PNPs) can be appended to targeting molecules that direct the drug cargos to cancer cells or tumors. Dr. Nguyen's PNPs are homogeneous, readily fabricated anticancer drug delivery vehicles. Potential advantages including the reduction of the dangers associated with conventional chemotherapy. In this sense, his PNPs can improve the efficacy of conventional cancer treatments and maintain the quality of life for cancer patients.