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Research Oversight

The Lurie Cancer Center provides oversight of all aspects of clinical research through several committees. These committees work collaboratively in this effort to provide comprehensive and robust review and monitoring oversight.

 Disease Teams

Provides an integrated, multidisciplinary approach to guide in the selection and prioritization of high-quality cancer research studies. Please review the Disease Team Charter for details. For questions, contact Alyssa Garcia

Team Leaders

Disease Team

Disease Team Leader

Disease Team Co-Leader

Early Phase Therapeutics

Deva Mehalingham, MD

Young Chae, MD

Hem - Leukemia

Jessica Altman, MD

Olga Frankfurt, MD

Hem - LPDs

Barbara Pro, MD

Leo Gordon, MD

Hem - MPNs

Brady Stein, MD

N/A

Hem - Transplant

Jayesh Mehta, MD

Kehinde Adekola, MD

TRIST - Skin

Jeffrey Sosman, MD

Sunandana Chandra, MD

TRIST - Lung

Malcolm DeCamp, MD

Nisha Mohindra, MD

TRIST - Head & Neck

Sandeep Samant, MD

Bharat Mittal, MD

TRIST - GI

Mary Mulcahy, MD

David Bentrem, MD

TRIST - GU

Maha Hussain, MD

Edward Schaeffer, MD

TRIST - Neuro-oncology

Priya Kumthekar, MD

Orin Bloch, MD

TRIST - Sarcoma

Mark Agulnik, MD

Jeffrey Wayne, MD

WC - Breast

William Gradishar, MD

Massimo Cristofanilli, MD

WC - Gynecological

Shohreh Shahabi, MD

Daniela Matei, MD

Documents

Disease Team Charter

Study Review Endorsement Form

Supplemental Clinical Trial Review Form

 Scientific Review Committee (SRC)

Evaluates all cancer-relevant research protocols, including the review of all protocol amendments.  Please see the SRC Charter for more details.

Members

Name

Specialty

Status

Kehinde Adekola, MD 
Core Member

Hematologic Malignancies 

Voting Member

Mark Agulnik, MD 
Member

Medical Oncology 

Voting Member

Jessica Altman, MD 
Alternate Member

Hematologic Malignancies 

Voting Member

Al Benson III, MD 
Chair

Medical Oncology 

Voting Member

Eric Donnelly, MD 
Core Member

Radiation Oncology 

Voting Member

Pedram Gerami, MD 
Core Member

Dermatology 

Voting Member

Borko Jovanovic, PhD 
Core Member

Biostatistics 

Voting Member

Masha Kocherginsky, PhD 
Alternate Member

Biostatistics 

Voting Member

Robert Lewandowski, MD 
Core Member

Radiology 

Voting Member

Daniela Matei, MD 
Core Member

Gynecological Oncology 

Voting Member

Maria Matsangou, MD 
Member

Medicine-Hematology/Oncology 

Voting Member

Joshua Meeks, MD 
Alternate Member

Translational Research, Urology 

Voting Member

John Nielsen, MD 
Scientific Review Coordinator

David Odell, MD, MMSc

Thoracic Surgery

Voting Member

Carolyn Passaglia, CCRP 

Clinical Research Operations

Tim Pearman, PhD
Alternate Member

Cancer Control and Survivorship 

Voting Member

Barbara Pro, MD 
Core Member

Hematologic Malingancies 

Voting Member

Alfred Rademaker, PhD 
Co-Chair

Biostatistics 

Voting Member

Renee Riphenburg Webb, MA, CCRC 

Research Administration

Sally Scherer, CCRA 

Interim Associate Director, Research Oversight System

Jonathan Strauss, MD 
Core Member

Radiation Oncology 

Voting Member

Victoria Villafor, MD 
Core Member

Medical Oncology 

Voting Member

David Walterhouse, MD

Pediatric Oncology

Voting Member

Amy Walz, MD 
Core Member

Pediatric Oncology

Voting Member

Tony Yang, MD 
Core Member

Translational Research in Solid Tumors 

Voting Member

Susan Yount, MD 
Core Member

Cancer Control and Survivorship 

Voting Member

Rotating Pharmacy Representatives

  • Colleen Czerniak, PharmD 
  • Marina Grishchenko, PharmD 
  • Kathryn O'Brien, PharmD 
  • Soniya Tambe, PharmD 

Rotating Pathology Representatives

  • Elena Aristide, CCRP 
  • Lauren Nielsen 

Documents

2017 Meeting Schedule

2018 Meeting Schedule

SRC Charter

Guidance on SRC Review Requirements

Low Accrual Policy

Data and Safety Monitoring Plan

No Waiver Policy

Trial Activation Diagram

Research Oversight Interactions Diagram

Reviewer Forms

 Data and Safety Monitoring Committee (DSMC)

Responsible for data and safety monitoring, monitoring of protocol compliance. 

Members

Name

Specialty

Status

Al B. Benson, III, MD, FACP, FASCO 
Member

Voting Member

Sonali Chaudhury, MD 
Co-Chair

Pediatric Hematology/Oncology 

Voting Member

Olga Frankfurt, MD 
Chair

Hematology/Medical Oncology 

Voting Member

Catherine Humphreys, MA, CCRC 
Member

Quality Assurance

Aparna Kalyan, MD 
Member

Developmental Therapeutics 

Voting Member

Jason Kaplan, MD 
Member

Developmental Therapeutics 

Voting Member

Nisha Mohindra, MD 
Member

Thoracic Oncology 

Voting Member

Carolyn Passaglia, CCRP 
Member

Clinical Research Operations

Sally Scherer, CCRA 
Member

Quality Control/Quality Assurance

Denise Scholtens, PhD 
Member

Biostatistics 

Voting Member

Mary Beth Tull, MS 
Member

Chemoprevention

Renee Webb, MA, CCRC 
Member

Cancer Center Administration

Jill Woodman, CCRP 
Member

Quality Assurance

Documents

Responsibilities

Administrative Guidelines & Processes

Publication Policies & Processes

Data Compliance Policies & Processes

Protocol Deviation Form

Serious Adverse Event (SAE) Form

Internal Data Compliance Policy

Participating Site Data Compliance Policy

Semi-Annual Report Template

Minimal/Moderate Semi-Annual Report 

 Clinical Trial Audit Committee (CTAC)

Responsible for the internal auditing program. 

Members

Name

Specialty

Status

Jessica Altman, MD 
Chair

Hematologic Malignancies 

Voting Member

Kehinde U.A. Adekola, MD 
Member

Hematologic Malignancies 

Voting Member

Marina Grishchenko, BCPS, RPH, PhD 
Member

Pharmacy

Voting Member

Catherine Humphreys, MA, CCRC 
Member

Quality Assurance

Aparna Kalyan, MBBS 
Member

Developmental Therapeutics 

Voting Member

Jason Kaplan, MD 
Member

Developmental Therapeutics 

Voting Member

Sheetal M. Kircher, MD 
Member

Translational Research in Solid Tumors 

Voting Member

Katherine McCarthy, CCRP 
Member

Quality Assurance

Carolyn Passaglia, CCRP 
Member

Clinical Research Operations

Mario Pineda, MD 
Member

Translational Research in Solid Tumors 

Voting Member

Sally Scherer, CCRA 
Member

Quality Assurance/Quality Control

Renee Webb, MA, CCRC 
Member

Cancer Center Administration

Jill Woodman, CCRP 
Member

Quality Assurance

Documents

Corrective Action Plan Template & Guidelines

Internal Audit Report Template

 Initial Submissions

To submit a cancer-relevant project to the SRC for approval, complete and submit the relevant forms to John Nielsen for initial processing.

Documents

Letter of Intent Template (must be submitted for all interventional investigator-initiated trials prior to protocol submission)

New Protocol Submission Form

Obtaining NOTIS Access (for sites that will not use NU IRB as their IRB of record)

IIT Templates (for assistance, contact Jennifer Kreutzer, Sabeeha Mukit or Emily Meyers)

 Revisions

The SRC receives and reviews revisions for projects that the committee initially approved. Revisions must include a summary of changes. All investigator-initiated studies, including those studies initiated by another site, must be SRC-approved prior to IRB submission. Industry-sponsored studies may be submitted to the SRC and IRB simultaneously. All revisions should be submitted to John Nielsen.

If the sponsor does not provide a summary of changes, please use template below.

Documents

Summary of Changes Template for Investigator-Initiated Studies

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