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Gastrointestinal: Rectum

An Open-Label, Dose Escalation, Phase 1, First-in-Human Study of TAK-659 in Adult Patients with Advanced Solid Tumor and Lymphoma Malignancies

Two of the main purposes of this study are to determine the side effects and risks of TAK-659 and the highest dose of TAK-659 that can be given to patients daily without causing side effects and risks that are too severe.

Status: Accepting New Patients
Principal Investigator: Jason Kaplan

A Phase III Clinical Trial Evaluating TheraSphere® in Patients with Metastatic Colorectal Carcinoma of the Liver who have Failed First Line Chemotherapy

The purpose of this study is to see if adding TheraSphere treatment at the beginning of second-line chemotherapy extends survival time and is safe.

Status: Accepting New Patients
Principal Investigator: Mary Mulcahy

A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab (IMC-1121B), in Advanced, K-ras Wild-type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy

The purpose of this study is to determine what good or bad effects the drug, ramucirumab, may have and to determine whether it is safe and effective for patients to receive.

Status: Accepting New Patients
Principal Investigator: Al Benson III

A Randomized Open-Label Pilot Trial to Evaluate the Safety and Efficacy of Repetitive Transcranial Magnetic Stimulation in Cancer Patients with Depression and Anxiety

The purpose of this study is to test the safety and tolerability of left- and right-sided rTMS as a treatment for depression in the cancer population.

Status: Accepting New Patients
Principal Investigator: Mehmet Dokucu

A Phase II/III trial of Neoadjuvant FOLFOX, with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision

The purpose of this study is to compare the effects, both good and bad, of the standard chemotherapy (5-fluorouracil/capecitabine) and radiation to chemotherapy using a combination regimen known as FOLFOX, (5-fluorouracil [5-FU}, oxaliplatin and leucovorin) prior to surgery.

Status: Accepting New Patients
Principal Investigator: Amy Halverson

Extended Duration Varenicline for Smoking among Cancer Patients: A Clinical Trial

The main purpose of this research study is to compare 12 versus 24 weeks of varenicline treatment, also known as Chantix®, for smoking cessation.

Status: Accepting New Patients
Principal Investigator: Brian Hitsman

last updated: Wed - March 29, 2017 - 06:55 PM

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