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Deputy Director - Francis J. Giles, MB, MD, FRCPI, FRCPath

Frank Giles

The Deputy Director is appointed by and reports to the Director of the Lurie Cancer Center. The position is responsible for oversight of clinical research and developmental therapeutics in the Lurie Cancer Center, including the coordination of all cancer-related clinical research services throughout the Lurie Cancer Center and Northwestern Medicine.

The Deputy Director plays a critical role in establishing the overall strategic direction, policy and priorities of the Lurie Cancer Center. He is integrally involved in all aspects of operations and functions as the senior leader in the Director's absence.

The Deputy Director provides leadership for clinical faculty recruitment and oversight of clinical research space in the Lurie Cancer Center. The Deputy Director chairs the Governance Committee of the Clinical Research Office and serves on the Clinical Cancer Center Executive Council and the Lurie Cancer Center Executive Committee.

Francis J. Giles, MB, MD, FRCPI, FRCPath is Professor of Medicine at Northwestern University Feinberg School of Medicine and Director of the Northwestern Medicine Developmental Therapeutics Institute. A cancer specialist with more than two decades of experience, Dr. Giles has led the development of novel drugs, immunotherapies, and other highly targeted approaches, including cancer-directed viruses, monoclonal antibodies, and molecularly directed agents. He has served as principal investigator on numerous national and international First in Human, Phase I, II, and III clinical studies of many novel agents, and holds numerous patents and technology licenses.

Dr. Giles has focused his clinical and research efforts on providing therapy for patients suffering from treatment-resistant or refractory cancer. He has pioneered the use of many agents that are now in regular use as targeted therapies for patients with cancer. Among his many accolades, Dr. Giles was recently elected as a Fellow of the European Academy of Cancer Sciences. He is also a Fellow of the Royal College of Physicians of Ireland and the Royal College of Pathologists (UK). He has over 500 peer-reviewed publications focused on oncology developmental therapeutics. Dr. Giles has particular interests in the mentoring of developmental therapeutics physician-scientists and in international collaborations across the bioscience spectrum.