Executive Committee - John D. Crispino, PhDThe Associate Director for Education and Training is appointed by and reports to the Director of the Lurie Cancer Center. The position is responsible for oversight and coordination of the Center's extensive professional education and training programs, including regional and national symposia. Public education programs are also organized by this division throughout the year. Intramural programs include weekly Lurie Cancer Center Grand Rounds, a weekly Tumor Cell Biology Seminar Series, an annual two day Distinguished Lecturer, annual Berlin Lecture, and an annual Scientific Poster Session. In addition to oversight of education programs, the Associate Director also oversees training activities for the Lurie Cancer Center. This includes coordinating the activities of students in the Cancer Biology track of the Integrated Graduate Program on the Chicago Campus, providing oversight for the training grants administered by the Lurie Cancer Center and coordinating efforts with other training programs such as Northwestern University's Medical Scientist Training Program and Master of Public Health Program. The Associate Director for Education and Training also directs significant philanthropic resources in support of graduate training. As a member of the Executive Committee and Leadership Group, the Associate Director for Education and Training also plays a key role in setting strategic direction, policy and priorities for the Cancer Center.
John Crispino, PhD, is Associate Professor of Medicine in the Division of Hematology/Oncology at Northwestern University's Feinberg School of Medicine. Dr. Crispino's laboratory studies the mechanisms of vertebrate blood cell development, performing basic research to define the transcription factors and cell cycle regulators that mediate lineage commitment and differentiation of mature blood cells. They also pursue translational studies to define the genetics of hematologic malignancies and to develop novel therapeutics for acute leukemia. Dr. Crispino's research is supported by multiple grants and awards. Most recently, he was awarded a National Institute of Health (NIH) Challenge Grant in Health and Science Research. Dr. Crispino's award is entitled: "Identification of altered molecular signatures of Down syndrome iPS cells." The project's long-term goal is to determine which of the microRNAs, mRNAs or methylation differences that are caused by trisomy 21 (Down Syndrome) contribute to aberrant hematopoiesis and the predisposition to leukemia in infants and children with Down Syndrome.
Dr. Crispino has published over 45 research articles in prestigious peer-review journals, including Nature Genetics, Journal of Experimental Medicine, Journal of Clinical Investigation, PNAS, Molecular and Cellular Biology and Blood. He currently serves on the editorial board of Blood, the Children's Oncology Group Laboratory Review Committee, the Eastern Cooperative Oncology Group Laboratory Review Committee and the American Society of Hematology Subcommittee on Myeloid Neoplasia. He is also the Chair of the Medical Advisory Board of the Leukemia Research Foundation and the Scientific Advisor of the Myeloproliferative Disease Foundation.